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Cimaterol

Cimaterol is a stimulant, a fat burner, and similar to clenbuterol in many ways& and different in some very important ones. Both clen and cimaterol are beta-adrenergic agonists, and thus are both anabolic as well as thermogenic (Reprod Nutr Dev. 1988; 28(1):61-84. Domest Anim Endocrinol. 1990 Oct;7(4):477-84) and also, stimulate your adrenal glands, increase your body temperature, raise your heart rate, etc& i.e. they mimic the "Fight or Flight" response quite well. Cimaterol, however may stimulate the beta-1, 2, and 3 receptors while clen only stimulates the beta 2 and 3 receptors. This may cause increased fat burning by cimaterol when compared with clenbuterol. Also, a far greater portion of brown adipose tissue is burned with the use of Cim over Clen, as far as I can tell.

clenbuterol,steroids,clen

Cimaterol stimulates both lypolisis (burning fat: the release of free fatty acids and glycerol) as well as inhibit lypogenesis (gaining fat: the incorporation of 14C into fatty acids from [14C]glucose) and may even do both more effectively than clen, possibly making it a more potent fat burner. In addition, it stimulates protein synthesis and thus could increase Fat Free Mass via this mechanism (Domest Anim Endocrinol. 1990 Oct;7(4):477-84) while at the same time burning fat. After a couple of weeks, however, the anabolic effects might lessen, as one study showed weight gain (with fat loss& ergo a PURE muscle gain concurrent with fat loss) halted after 14 days (J Anim Sci. 1992 Jan;70(1):115-22.). Energy metabolism has been shown to be greatly increased with Cim as well( Am J Physiol. 1988 Dec;255(6 Pt 2):R952-60). Cimaterol also stimulates blood flow and causes acute mobilization of nitrogen (alanine), significantly increases amino acid uptake in muscles, and mobilizes lactic acid out of muscles (J Anim Sci. 1998 Apr;76(4):988-98.). Thus, it may not have the athletic performance (endurance and possibly speed) decreasing effects of clen (which Ive written about and referenced studies about previously, so I wont get into that here& .its beyond the scope of this article). This is pure speculation on my part, and Cim may still have some of the performance decreasing effects of clen, but as other beta-andrenergic-agonists like ephedrine dont, I see no reason to think Cim does (as I havent read any studies which indicate this). In any case, alot of the studies Ive read and compared with those on Clenbuterol seem to indicate that Cimaterol is actually more potent for fat burning than clen is.

Ok...so now you know what I have to say about Cimaterol, lets see what some other people have said...

Heres Dan Duchaine (R.I.P.) had to say about Cimaterol:

"Until some new synthetic beta-3 agonist is commercially available, the beta agonist of choice is still clenbuterol (although the STRONGER cimaterol is available as a research chemical in the U.S.)."

Doug Kalman (author of "Fat Attack)" has written about Cimaterol, and said:

"Though its yet to be tested in humans, animal studies have determined that Cimaterol is a more powerful beta-agonist than clenbuterol, promotes protein retention and accretion, and has shown powerful anti-catabolic properties in cases of cancer or burns."

So yeah, not only is this stuff a great fat-burner, its anti-catabolic.

Looks promising, huh? Unfortunately, it down regulates the beta receptors just as clen does (J Anim Sci. 1992 Jan; 70(1):115-22.) so a 3 week on 1 week off type of schedule may be appropriate, as would the addition of Ketotifen after ever 3 weeks (and not going off the cimaterol& so in 4 weeks on cimaterol, every 4th week youd be adding in 2-3 mgs of Ketotifen every night before you go to bed). You could also use 50mgs of Banadryl instead of the Ketotifen, in the same manner.

As with any new drug, caution should be taken with this stuff.

A dose of 0.15 milligram per kilogram administered subcutaneously is the standard dose in a lot of human studies, so Id be comfortable trying that dose myself, but Id prefer a tablet (which is also available). Thats a fraction of any sort of dangerous dose.

Cimaterol, LD50:

    1973 mg/kg (male)
    and 1745 mg/kg (female)



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