Methosarb
(calusterone)
Methosarb Description:
Methosarb, a.k.a. calusterone, is a uniquely modified version of testosterone with dual alterations. It possesses one added methyl group at carbon 7-beta which essentially deactivates its anabolic and androgenic effects, and another one at carbon 17-alpha which permits the drug to pass through the liver and into the bloodstream without being deactivated, thereby making it effective for oral administration.
Methosarb was developed as a less, near non-toxic, alternative to traditional anabolic steroids for the treatment of inoperable and metastatic breast cancer in both men and postmenopausal women.
Methosarb Form:
This steroid came in 50 mg tablets, but is no longer manufactured as a prescription medication.
Methosarb Indications/Purpose:
This extremely unique drug, barely even warrants being described as an anabolic steroid or androgen. Its substantial alteration at carbon 7-beta, renders it virtually ineffectual for anabolic and performance enhancement purposes. It is therefore not recommended for such uses, even as a supporting anabolic cycle ingredient.
Although never FDA approved for men, their therapeutic dosages would be comparable to the 200 mg/day (range of 150-300 mg/day) recommended for women, which is often enough to keep blood serum levels well above baseline with this particular drug.
Methosarb Side Effects:
Methosarb produces zero aromatization, so you can expect to be free from estrogenic side effects (those due to increases in estrogen estradiol, prolactin, progesterone, or progestin) which generally include increased water retention, body fat gain, and gynecomastia (which is actually due to the testosterone and estrogen ratio imbalance).
Androgenic side effects, those having to do with male sexual characteristics, are also not anticipated with this particular drug. However, should they occur due to slightly elevated testosterone levels, they would likely produce oily skin, acne, body/facial hair growth, and possibly mild testicular atrophy (temporary reduction in the size of your testicles). Androgen drug use of any kind is also known to accelerate balding, but only in men with a genetic predisposition for hair loss. In other words, if youre losing or going to lose your hair then it can speed up the process, but it is never the primary cause of hair loss.
Methosarb Chemical Composition
17 beta-OH-7 beta, 17 alpha-dimethyl-androst-4-ene-3-one
17-beta-hydroxy-7-beta, 17-dimethylandrost-4-ene-3-one
7 beta, 17 alpha-dimethyltestosterone
Molecular Weight: 316.478
Formula: C21H32O2
Melting Point (base): 128 oC
Manufacturer: Not Manufactured
Effective Dose (Men): Approx. 200 mg/day (Not FDA approved For Men)
Effective Dose (Women): Approx. 200 mg/day
Half-Life: Unknown
Detection Time: Unknown
Anabolic/Androgenic Ratio: Unknown but virtually none
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