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Testosterone Enanthate

Testosterone Enanthate is probably the most commonly used form of testosterone by both athletes and bodybuilders alike. Further, in the United States, it is one of the most commonly prescribed testosterone compounds for the treatment of low testosterone or andropause conditions; however, Testosterone Cypionate is the most commonly prescribed when an injectable form is offered. Extremely effective for building muscle and enhancing strength, Testosterone Enanthate can also help with losing fat and it comes with some great news; its very cheap and widely available.

In-order to understand exactly how Testosterone Enanthate (commonly referred to as "test-e") builds muscle and burns fat, first well take a look at androgens and what they do in the body. You see, hormones are substances secreted by one cell that has an effect on the functions of another cell. Testosterone is manufactured in the Leydigs cells of the testes (in men) and the adult male produces between 2.5 and 11mgs of Test per day.

Testosterone induces changes in shape, size and also can change the appearance and the number of muscle fibers(7). Androgens like testosterone, which is exactly what Testosterone Enanthate is can protect your hard earned muscle from the catabolic (muscle wasting) glucocorticoid hormones(8), thus inhibiting their ability to send a message to muscle cells to release stored protein. Remember, testosterone sends a message to muscle cells to store more contractile protein (called actin and myosin); glucocorticoid hormones send the opposite message. In addition, Testosterone Enanthate has the ability to increase erythropoiesis (red blood cell production) in your kidneys(9), and a higher Red Blood Cell (RBC) count will improve endurance via better oxygenated blood. More RBCs can also improve recovery from strenuous physical activity. Of course, aggression levels can rise dramatically with the use of exogenous testosterone (15); however, its important to remember aggression in of itself is not a bad thing; what we do with it is what makes it right or wrong. At any rate, Testosterone Enanthate holds no mind altering traits or nature whatsoever.

Testosterone Treatment only $199/month All-Included All of these great benefits are to be had with the use of Testosterone Enanthate alone, but realistically, it will in most cases be part of a cycle containing one or more other steroids. People who are bulking will probably choose Deca Durabolin or Trenbolone compounds, and of course the possibility of powerful oral steroids like Anadrol or Dianabol. Then we have those who are cutting, and they will probably steer towards Equipoise and once again Trenbolone, along side compounds such as Anavar, Masteron, Winstrol and perhaps Primobolan; all are solid options. Very often users will administer Testosterone Enanthate once or twice a week, but blood levels are still above baseline with this steroid at around day eight (16).Common wisdom holds that the testosterone portion of any such cycle should be equal to or greater than any other injectable steroids portion (on a mg basis); however, this isnt always needed, but its a good rule of thumb to ensure no low testosterone condition exists.

As you may have suspected, Testosterone Enanthates anabolic/androgenic effects are dose dependent; the higher the dose the higher the muscle building effect(10). Lets take a look at exactly what kind of results we can expect from administration of Testosterone Enanthate:

Effects of 20 weeks of GnRH agonist plus Testosterone Enanthate administration on relative changes (mean SEM) in total LBM (A), appendicular LBM (B), and trunk LBM (C) (percent change from baseline) measured by DEXA. P values are results for ANOVA: *, P < 0.05 vs. all other dose groups for the multiple comparison tests using Student-Newman-Keuls; a, P < 0.05 vs. zero change.(11)
 

Testosterone Enanthate

This chart shows that the subjects in this test made a roughly 15% gain in Lean Body Mass from 20 weeks of 600mgs/week of Testosterone Enanthate. That's pretty impressive, but the following set of charts is even more telling:

 Testosterone Enanthate

Change in fat-free mass (A), fat mass (B), leg press strength (C), thigh muscle volume (D), quadriceps muscle volume (E), sexual function (F), insulin-like growth factor I (G), and prostate-specific antigen (H). Data are means SE. *Significant differences from all other groups (P < 0.05); significant difference from 25-, 50-, and 125-mg doses (P < 0.05); +significant difference from 25- and 50-mg doses (P < 0.05); and significant difference from 25-mg dose (P < 0.05). (14)

Now this is very interesting. You'll note that the most fat was lost by the group in this study who used the highest dose of Testosterone Enanthate (600mgs/week), and the most Fat Free mass, Strength and Muscle Volume was gained, when compared to any of the lower doses studied (14). Basically, the more Testosterone Enanthate you use (and this holds true for almost all steroids), the more gains you'll get! Of course, that the previous statement will ruffle some feathers in the "less is more" club, but that's simply too bad; more Testosterone Enanthate = more muscle, more strength, more size, and less fat.

Did the men in this study experience side effects at the 600mg dose? Well, HDL cholesterol was lowered (but not total cholesterol or triglyceride levels), and two guys got Acne. Not exactly cause for a Senate Investigation. (14)

Of course, the usual nasty side effects you can get from any form of injectable testosterone are possible with Testosterone Enanthate; gynecomastia, water retention and high blood pressure are all possible, but they are very overstated or controllable in many instances.

A large percentage of those side effects occur from the body's ability to turn Testosterone Enanthate, which is again simply a testosterone hormone into estrogen via a metabolic pathway mediated by the aromatase enzyme. This process, known as aromatization causes a portion of testosterone to be converted to estrogen. Aromatase Inhibitors, Anastrozole (Arimidex) and Letrozole (Femara) can combat this very effectively, and are usually necessary with doses over a gram per week, and often recommended with lower performance doses.

Now that we understand Testosterone Enanthate, lets talk about cost. You should be paying no more than $75 for a 10cc bottle of Testosterone Enanthate, dosed at 250mgs/ml. Of course, as usual, prices fluctuate depending on the brand or supplier, but $75 is a standard underground label range. Even so, you can easily obtain Testosterone Enanthate in high quality form from an underground lab for even less, as little as $40 per 10ml, but youll need to do some digging. As for human grade forms, $100+ for 10ml is quite common, especially if its purchased directly from the pharmacy; however, with the right large supplier you can easily find $60 pricing; even Testoviron Depot, considered one of the best Testosterone Enanthate compounds on earth has been found for as little as $5 to $7 per ampule.

Testosterone Enanthate Steroid Profile

  •     17b-hydroxy-4-androsten-3-one
  •     Testosterone base + Enanthate ester
  •     Molecular Weight: 412.6112
  •     Molecular Weight (base): 288.429
  •     Molecular Weight (ester): 130.1864
  •     Formula (base): C19 H28 O2
  •     Formula (ester):C7 H12 O
  •     Melting Point (base): 155
  •     Manufacturer: Various
  •     Effective Dose (Men): 300-2000mg+ week
  •     Effective Dose (Women): Not recommended
  •     Active life: 10.5 days
  •     Detection Time: 3 months
  •     Anabolic/Androgenic ratio:100/100.

Testosterone Enanthate References:

  1. Am J Physiol. 1998 Nov;275(5 Pt 1):E864-712
  2. J Clin Endocrinol Metab. 1997 Feb;82(2):407-13
  3. Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E601-7.
  4. Curr Opin Clin Nutr Metab Care. 2004 May;7(3):271-7.
  5. Curr Pharm Biotechnol. 2004 Oct;5(5):459-70.
  6. J Clin Endocrinol Metab. 2004 Oct;89(10):5245-55.
  7. Anat Histol Embryol. 2003 Apr;32(2):70-9.
  8. J Lab Clin Med. 1995 Mar;125(3):326-33.
  9. Zhonghua Nan Ke Xue. 2003;9(4):248-51
  10. J Clin Endocrinol Metab. 2003 Apr;88(4):1478-85
  11. J Clin Endocrinol Metab. 2004 Feb;89(2):718-26.
  12. Am J Physiol. 1998 Jun;274(6 Pt 1):C1645-52.
  13. Biochim Biophys Acta. 1995 May 11;1244(1):117-20.
  14. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81.
  15. Health Psychol. 1990;9(6):774-91.
  16. Fertility and Sterility 33.

Testosterone Enanthate Video


 




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