Chemical Name: Prosta-5,13-dien-l-oic acid,
9,11,15-trihydroxy-, (5Z,9a,l la,13,15S)-, compd. with 2-
Molecular Weight: 360.53 g/mol
Protein Binding: N/A
Half-Life: A few minutes
Manufacturer: Pharmacia & Upjohn, varied
Active Ingredient: Dinoprost tromethamine
Inactive Ingredients: Water, benzyl alcohol
Lutalyse is the brand name for dinoprost tromethamine, a sterile solution used for several cattle, swine and mare birthing & birth-related medical conditions. More specifically, dinoprost is used for: estrus synchronization, as well as the treatment of unobserved (silent) estrus, and pyometra (chronic endometritis) in cattle; abortion of feedlot and other non-lactating cattle; parturition induction (induced birthing labor) in swine and; for controlling the timing of estrus in estrous cycling mares and clinically anestrous mares that have a corpus luteum.
Dinoprost tromethamine is a white or slightly off-white crystalline powder that is readily soluble in water at room temperature. Lutalyse comes in multiple delivery systems including intra-amniotic (injected into the amniotic fluid), intravenous, and intramuscular. It is often found in intramuscularly injectable doses of 5 mg/ml, in 5-100 ml vials. Each ml contains 5 mg dinoprost along with water, and 9.45 mg of the preservative benzyl alcohol.
For bodybuilding/athletic purposes Lutalyse holds a dual role in that it: 1) possesses strong protein synthesis which not only greatly accelerates muscle building, but also appears to have spot/localized (specially where injected) muscle enhancing effect on both size & definition and; 2) is clinically proven to incite lipolysis (fat burning and mobilization) within fat cells.
With a fast-acting response time, Lutalyse is reported to return desired results to in as little as two weeks. However, multiple studies have been run on the human implications for this drug, many of which remain conflictingly inconclusive.
Although Lutalyse is often taken orally by pregnant women to induce labor, its used by bodybuilders and athletes for the above reasons, as well as to increase the size of lagging body parts. It should be administered slowly and pyramided upwards from .5 mg per injection/day, by increments of .5 mg/day, until the desired dosage is reached. Lutalyses half-life varies based on delivery method, but according to Pharmacia & Upjohn, the intramuscular biological half-life of dinoprost tromethamine is no more than a few minutes, a figure arrived at based on both cow and rat serum measures taken during the 24 hours after the administration of 0 to 250 mg dosages.
There are a variety of possible bronchial and gastrointestinal conditions associated with the use of Lutalyse, but the most prominent athlete specific (those taking it for performance and physique enhancing purposes) side effects include: injection site pain; flu-like symptoms; diarrhea; abdominal/stomach pain; false sense of urgency toward enuresis (uncontrollable urination) and encopresis (uncontrollable defecation); malaise and; general bodily discomfort.
Though primarily manufactured in the US by Pharmacia & Upjohn as Lutalyse, dinoprost has multiple manufacturers worldwide and is available via prescription in several countries.
Lutalyse would be very effective if added to anabolic cycles geared towards definition, which included compounds like Anavar, Trenbolone, testosterone (cypionate, propionate, and enanthate), Winstrol, Halotestin, Primobolan, Oral Turinabol, Deca-Durabolin, and Equipoise.