TB-500 is a peptide fragment hormone that is primarily used in the treatment of various muscle injuries or pain caused by inflammation. There is very little official human data available for this product; however, it has been a longtime hormone used in racehorses. TB-500, although synthetic, serves to act as a synthetic form (loosely) of Thymosin Beta-4 (TB-4). TB-500 is not TB-4; although very commonly confused as TB-4, it is designed to provide the benefits of the naturally occurring thymus produced hormone.
The thymus gland as well as in various localized cells in the human body produces thymosin Beta-4 (TB-4). TB-4 is found in cytoplasm in high levels of concentration as well as in wound fluid. TB-500 is designed to promote the actionable area – the part of TB-4 that promotes healing. More importantly, manufacturing TB-500, despite not being TB-4 is possible while the latter is extremely difficult.
The primary purpose of TB-500 lies in its ability to promote the upregulation of cells in the body. Upregulation increases the cell’s sensitivity to action, specifically in proteins such as actin. This action helps to regulate inflammation in injured areas of the body as well as provide new blood vessel pathways. Of interesting note - TB-500 possesses a very low molecular weight allowing it to carry a high level of mobility in the body. Simply put, TB-500 can travel long distances through the body, virtually to all locations. TB-500 does not have to be administered to the injured area but will find its way to all injured areas regardless of administrated location.
In the world of performance enhancement, TB-500 is not meant to be used to bulk, cut, lose fat or increase strength. This is a peptide hormone that is designed to promote healing, specifically the healing of wounded or injured areas of the body. TB-500 can be used to treat muscle tears or strain, tendon inflammation and even skin injuries. This peptide will not cause instant healing of an injured area. If a muscle is torn it is torn, but use of TB-500 will in many cases speed up the healing process. For nagging injuries, those that don’t keep the individual out of the gym but slow his progress, it may provide the edge he needs to continue his training without it being diminished.
The effects of TB-500 have also been linked to hair growth, specifically the reversal of hair loss caused by male-pattern baldness. However, how significant this effect is and how much truth it holds scientifically is still highly questionable as no official data exist. The only data on hair growth is anecdotal.
The side effects of TB-500 are lacking in official capacity as the peptide has been primarily used in horses since the early 1980’s with almost no human data available. As with any injectable medication, especially peptides, the most common side effect will be skin irritation at the injected site. However, this does appear to be less common with TB-500 as compared to other injectable peptides in terms of anecdotal reports by users. Headaches and other ill-like symptoms also appear to be very rare.
TB-500 comes in freeze-dried (lyophilized) form and must be reconstituted with bacteriostatic water for administration. The most common dosing range in human use is 2.0 to 2.5mg of TB-500 two times per week for approximately 4-6 weeks. Once the 4-6 weeks of use is complete, once the injured area has improved, some users will reduce to one to two injections per month for injury prevention. Many users report greater muscle flexibility when using TB-500, thereby reducing further injury potential.
Higher doses of TB-500, those beyond 2.0-2.5mg twice per week, there is no data available to support how much stronger such dosing plans will be. There is very little data to support the lower doses beyond anecdotal but even less when it comes to higher doses. As healing and injury prevention is the primary point of use and the 2.0-2.5mg plans seem to carry a high rate of success, this does tend to lend to higher doses being unnecessary.
You can buy TB-500 online from numerous online chemical research companies. Research companies that provide non-controlled substances such as ancillaries, erectile dysfunction meds and various peptides often carry TB-500. You can also buy TB-500 online from various equestrian supply companies. However, there is no veterinarian grade form of the peptide as exists with certain anabolic steroids like Equipoise (Boldenone). A research or equestrian company simply sells it or they don’t. The only true concern is purity, meaning no outside chemicals or bacteria existing in the compound.
TB-500 is one of the more interesting peptides on the market due to its potential for directly healing injuries. Some data, although limited, has also shown the peptide may in fact have heart-healing properties, particularly that of ventricle hypertrophy. However, because full data on TB-500 is so limited, it’s very hard to give an honest review beyond “he said she said.” But it’s also difficult to ignore that many users do tend to heal much faster with it than without, and in some cases, faster than would seem possible.
It’s also important to note that TB-500 users often report better results when used with Human Growth Hormone (HGH) or Human Growth Hormone Releasing Hormones (HGRH) compounds. This isn’t surprising when Growth Hormone (GH) is one of the primary healing tools we have at our disposal. It’s hard to say how much faster healing will be with or without a GH product, but what we know of GH (there is massive amounts of data available on GH) it only makes sense that it would be much faster.